Kojic acid
SIGMA/K3125
Synonym: 2-
CAS Number: 501-30-4
Empirical Formula (Hill Notation): C6H6O4
Molecular Weight: 142.11
EC Number: 207-922-4
MDL Number: MFCD00006580
Linear Formula: C6H6O4
Product Type: Chemical
| assay | ≥98.5% (HPLC) |
| form | powder |
| InChI | 1S/C6H6O4/c7-2-4-1-5(8)6( |
| InChI key | BEJNERDRQOWKJM-UHFFFAOYSA |
| mp | 152-155 °C (lit.) |
| Quality Level | 200  |
| SMILES string | OCC1=CC(=O)C(O)=CO1 |
| Application: | Kojic acid has been used: • as an inhibitor of tyrosinase in guinea pigs pigmented hyperopic (PH) • as a reference inhibitor standard for screening tyrosinase inhibition • as a positive control for inhibition of tyrosinase in B16F10 melanoma cells |
| Biochem/physiol Actions: | Kojic acid is derived from some fungal species such as, Aspergillus, Acetobacter and Penicillium.. It halts melanin synthesis by inhibiting tyrosinase enzyme. It is used in the preparation of skin whitening cosmetics. However, kojic acid usage is minimal in cosmetics, as it induces skin irritation by its unstability and cytotoxic nature during long storage. It is an antioxidant and elicits radioprotective effects on chelating with manganese and zinc. |
| Biochem/physiol Actions: | Tyrosinase inhibitor. |
| Packaging: | 5, 10, 25 g in poly bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.5% (HPLC) |
| mp | 152-155 °C (lit.) |
| UNSPSC | 12352106 |