α-Ketoglutaric acid
SIGMA/K1750 - ≥98.5% (NaOH, titration)
Synonym: 2-Oxoglutaric acid; 2-Oxopentanedioic acid
CAS Number: 328-50-7
Empirical Formula (Hill Notation): C5H6O5
Molecular Weight: 146.10
EC Number: 206-330-3
MDL Number: MFCD00004165
Linear Formula: HOOCCH2CH2COCOOH
Product Type: Chemical
| assay | ≥98.5% (NaOH, titration) |
| form | powder |
| InChI | 1S/C5H6O5/c6-3(5(9)10)1-2 |
| InChI key | KPGXRSRHYNQIFN-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | OC(=O)CCC(=O)C(O)=O |
| solubility | water: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow |
| storage temp. | 2-8°C |
| Application: | α-Ketoglutaric acid (α-KG) has been used: • to study its effects on swine fecal microflora in an in vitro fermentation system • to study its effects on the activation of CD8+ T-cells • as a substrate in glutamate oxaloacetate transaminase (GOT2) mitochondrial lysate assay |
| Biochem/physiol Actions: | α-Ketoglutaric acid (α-KG) has a wide range of applications in the animal feed, food, pharmaceutical and fine chemistry industries. |
| General description: | α-Ketoglutaric acid (α-KG) is produced in the tricarboxylic acid cycle. |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 100 g in poly bottle |
| Symbol | GHS05 |
| Signal word | Danger |
| Hazard statements | H318 |
| Precautionary statements | P280 - P305 + P351 + P338 + P310 |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.5% (NaOH, titration) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352204 |


