Idebenone
SIGMA/I5659 - ≥98% (HPLC)
Synonym: 2-
CAS Number: 58186-27-9
Empirical Formula (Hill Notation): C19H30O5
Molecular Weight: 338.44
MDL Number: MFCD00274552
Linear Formula: C19H30O5
Product Type: Chemical
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C19H30O5/c1-14-15(12-1 |
| InChI key | JGPMMRGNQUBGND-UHFFFAOYSA |
| Quality Level | 200 ![]() |
| SMILES string | O=C(C(OC)=C1OC)C(CCCCCCCC |
| solubility | methanol: 50 mg/mL, clear to slightly hazy |
| storage temp. | room temp |
| Application: | Idebenone has been used: • to treat mutant myocilin (mMYOC) cells for drug treatment assay • to validate C2C12 secondary cell screening assay • to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs |
| Biochem/physiol Actions: | A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen. |
| Biochem/physiol Actions: | Idebenone is used in the treatment of visual impairment in adolescents and adults with Leber′s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress. |
| General description: | Idebenone is a short-chain benzoquinone drug. |
| Packaging: | 100 mg in poly bottle |
| Packaging: | 25 mg in glass insert |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352204 |

