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Idebenone

SIGMA/I5659 - ≥98% (HPLC)

Synonym: 2-(10-hydroxydecyl)-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione

CAS Number: 58186-27-9
Empirical Formula (Hill Notation): C19H30O5
Molecular Weight: 338.44
MDL Number: MFCD00274552
Linear Formula: C19H30O5
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-I5659-25MG 25 mg
$173.00
1/EA
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45-I5659-100MG 100 mg
$551.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I5659-25MG.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: I5659-100MG

 

assay ≥98% (HPLC)
form powder
InChI 1S/C19H30O5/c1-14-15(12-10-8-6-4-5-7-9-11-13-20)17(22)19(24-3)18(23-2)16(14)21/h20H,4-13H2,1-3H3
InChI key JGPMMRGNQUBGND-UHFFFAOYSA-N
Quality Level 200 
SMILES string O=C(C(OC)=C1OC)C(CCCCCCCCCCO)=C(C)C1=O
solubility methanol: 50 mg/mL, clear to slightly hazy
storage temp. room temp
Application: Idebenone has been used:
• to treat mutant myocilin (mMYOC) cells for drug treatment assay
• to validate C2C12 secondary cell screening assay
• to treat obese mice, to test whether idebenone and CoQ10 bind directly to peroxisome proliferator-activated receptor (PPAR)LBDs, His-tagged PPARα, δ and γ LBDs

Biochem/physiol Actions: A short-chain Coenzyme Q analog that enhances superoxide formation, presumably by mediating electron transfer from N2 to oxygen.
Biochem/physiol Actions: Idebenone is used in the treatment of visual impairment in adolescents and adults with Leber′s hereditary optic neuropathy (LHON). It serves as an antioxidant. It helps to guard the heart muscle against oxidative stress.
General description: Idebenone is a short-chain benzoquinone drug.
Packaging: 100 mg in poly bottle
Packaging: 25 mg in glass insert
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352204

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