Interleukin-5 human
SIGMA/I5273 - recombinant, expressed in baculovirus infected Sf21 cells, ≥97% (SDS-PAGE), lyophilized powder, suitable for cell culture
Synonym: IL-5
MDL Number: MFCD00163946
Product Type: Chemical
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| assay | ≥97% (SDS-PAGE) |
| biological source | human |
| concentration | 0.5-10 ng/mL |
| form | lyophilized powder |
| impurities | endotoxin, tested |
| mol wt | 32-34 kDa |
| packaging | pkg of 5 μg |
| potency | 0.1-0.5 ng/mL ED50 |
| Quality Level | 200  |
| recombinant | expressed in baculovirus infected Sf21 cells |
| storage temp. | −20°C |
| technique(s) | cell culture | mammalian: suitable |
| UniProt accession no. | P05113  |
| Biochem/physiol Actions: | IL-5 (interleukin-5) is a maturation and differentiation factor for eosinophils. Thus, it is associated with allergy and related disorders. IL-5 association with its receptor causes activation of MEK/ERK (mitogen activated protein kinase kinase/extracellular-regu |
| Biochem/physiol Actions: | Interleukin-5 is a product of activated T lymphocytes and exhibits activity on eosinophils, B cells and thymocytes. Synonyms or biological activities attributed to IL-5 include: EDF (eosinophil differentiating factor), BCGF-II (B cell growth factor-II), TRF (T cell replacing factor), IgA-EF (IgA enhancing factor) and EO-CSF (eosinophil colony stimulating factor). Natural IL-5 is a 45-50 kDa dimeric glycoprotein, although glycosylation is not required for activity. Human and mouse IL-5 exhibit homology at the nucleotide and amino acid levels and show species cross-reactivity. |
| Physical form: | Lypholized from 0.2 um filtered solution of PBS, pH 7.2 with 50 ug BSA. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (SDS-PAGE) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |