Iodoacetamide
SIGMA/I5161
CAS Number: 144-48-9
Empirical Formula (Hill Notation): C2H4INO
Molecular Weight: 184.96
EC Number: 205-630-1
MDL Number: MFCD00008028
Linear Formula: ICH2CONH2
Product Type: Chemical
| assay | ≥99% (NMR) |
| biological source | synthetic |
| form | powder |
| InChI | 1S/C2H4INO/c3-1-2(4)5/h1H |
| InChI key | PGLTVOMIXTUURA-UHFFFAOYSA |
| mp | 92-95 °C (lit.) |
| Quality Level | 400 ![]() |
| SMILES string | NC(=O)CI |
| solubility | H2O: 0.5 M, clear, colorless |
| storage temp. | 2-8°C |
| suitability | suitable for manufacturing use |
| Biochem/physiol Actions: | Iodoacetamide acts as an alkylating reagent for cysteine residues in peptide sequencing. It is an irreversible inhibitor of enzymes with cysteine at the active site. It reacts much more slowly with histidine residues, but that activity is responsible for inhibiting ribonuclease. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program ![]() Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 25, 100 g in glass bottle |
| Symbol | ![]() GHS06,GHS06 |
| Signal word | Danger-Danger |
| Hazard statements | H301 - H315 - H317 - H319 - H335 - H301 - H315 - H317 - H319 - H335 |
| Precautionary statements | P261 - P264 - P280 - P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338 - P301 + P310 - P302 |
| Hazard Codes | T |
| Risk Statements | 25-42/43-53 |
| Safety Statements | 22-36/37-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Purity | ≥99% (NMR) |
| mp | 92-95 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352202 |


