Sodium iodoacetate
SIGMA/I2512 - ≥98%
Synonym: Iodoacetic acid sodium salt
CAS Number: 305-53-3
Empirical Formula (Hill Notation): C2H2INaO2
Molecular Weight: 207.93
EC Number: 206-165-7
MDL Number: MFCD00002686
Linear Formula: ICH2COONa
Product Type: Chemical
| assay | ≥98% |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C2H3IO2.Na/c3-1-2(4)5; |
| InChI key | AGDSCTQQXMDDCV-UHFFFAOYSA |
| mp | 208 °C (dec.) (lit.) |
| Quality Level | 200 ![]() |
300 ![]() |
|
| SMILES string | [Na+].[O-]C(=O)CI |
| solubility | H2O: 100 mg/mL |
| storage temp. | −20°C |
| Application: | Reagent for the modification of cysteine residues in proteins. |
| Application: | Reagent for the modification of cysteine residues in proteins. Used in protein sequencing (including by Sanger in sequencing bovine insulin) to prevent oxidation of -SH sidechains. |
| Application: | Reagent for the modification of cysteine residues in proteins. Used to induce animal osteoarthritis model system, which mimics both symptoms and histopathology of the human disease. |
| Biochem/physiol Actions: | Used to induce osteoarthritis-like lesions and functional impairment in rats, for testing of chondroprotective agents and diagnostic imaging techniques. |
| Packaging: | 25, 100 g in glass bottle |
| Symbol | ![]() GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H314 |
| Precautionary statements | P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 25-37/38-41 |
| Safety Statements | 26-39-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 406.4 °F |
| Flash Point(C) | 208 °C |
| Purity | ≥98% |
| mp | 208 °C (dec.) (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |



