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L-Homocysteine thiolactone hydrochloride

SIGMA/H6503 - ≥98% (TLC)

Synonym: L-2-Amino-4-mercaptobutyric acid 1,4-thiolactone hydrochloride

CAS Number: 31828-68-9
Empirical Formula (Hill Notation): C4H7NOS · HCl
Molecular Weight: 153.63
EC Number: 250-824-1
MDL Number: MFCD00065494
Linear Formula: C4H7NOS · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-H6503-100MG 100 mg
 $126.00
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45-H6503-250MG 250 mg
 $211.00
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45-H6503-1G 1 g
 $684.00
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45-H6503-5G 5 g
 $2480.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H6503-1G.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: H6503-5G.

 

application(s) detection
peptide synthesis
assay ≥98% (TLC)
color white
form powder
InChI 1S/C4H7NOS.ClH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H/t3-;/m0./s1
InChI key ZSEGSUBKDDEALH-DFWYDOINSA-N
mp 185 °C
Quality Level 200 
SMILES string Cl[H].N[C@H]1CCSC1=O
Application:

  • Effects of DL-homocysteine thiolactone on cardiac contractility, coronary flow, and oxidative stress markers in the isolated rat heart: This investigation demonstrates the effects of DL-homocysteine thiolactone on heart function, offering insights into its use in cardiovascular research and potential therapeutic applications (Zivkovic et al., 2013 ).

  • Homocysteine is a novel risk factor for suboptimal response of blood platelets to acetylsalicylic acid in coronary artery disease: The study explores how L-homocysteine thiolactone could affect platelet responses in therapy for coronary artery diseases, pointing to its importance in cardiovascular therapeutics (Karolczak et al., 2013 ).
Biochem/physiol Actions: L-Homocysteine thiolactone, an amine reactive agent, is used to study post-translational modification of proteins, especially at lysine residues.
Packaging: 1, 5 g in glass bottle
Packaging: 100, 250 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (TLC)
mp 185 °C
UNSPSC 12352209

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