L-Histidine

SIGMA/H6034 - suitable for cell culture, meets EP, USP testing specifications, from non-animal source

Synonym: (S)-2-Amino-3-(4-imidazolyl)propionic acid; NSC 137773

CAS Number: 71-00-1
Empirical Formula (Hill Notation): C₆H₉N₃O₂
Molecular Weight: 155.15
EC Number: 200-745-3
MDL Number: MFCD00064315
Linear Formula: C₆H₉N₃O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-H6034-10MG	10 mg	$30.10 1/EA	Add To Favorites
45-H6034-25G	25 g	$65.50 1/EA	Add To Favorites
45-H6034-100G	100 g	$215.00 1/EA	Add To Favorites
45-H6034-1KG	1 kg	$1330.00 1/EA	Add To Favorites

ATR-IR Spectra for (S)-2-Amino-3-(4-imidazolyl)propionic acid.

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: H6034-100G

Properties
Descriptions
Safety Info.
Basic Data

agency	meets EP testing specifications
	meets USP testing specifications
application(s)	peptide synthesis pharmaceutical (small molecule)
assay	98.5-101.0%
biological source	non-animal source
cation traces	As: ≤1 ppm
	Fe: ≤10 ppm
	NH₄⁺: <0.02%
color	white to off-white
form	powder
functional group	(Imidazole)
	amine
	carboxylic acid
impurities	endotoxin, tested
InChI	1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChI key	HNDVDQJCIGZPNO-YFKPBYRVSA-N
mp	282 °C (dec.) (lit.)
optical activity	[α]20/D 12.0 to 12.8 °, c = 11 in 6 M HCl
	[α]25/D 12.6 to 14.0 °, c = 11 in 6 M HCl
Quality Level	300
SMILES string	N[C@@H](Cc1c[nH]cn1)C(O)=O
solubility	H₂O: 50 mg/mL
storage temp.	room temp
technique(s)	cell culture \| mammalian: suitable

Application:	L-histidine has been used as a component in agar plates containing 5-fluorocytosine (5-FC) for the selection of yeast transformants. It has also been used as a component of adult mouse keratinocyte growth medium.
Biochem/physiol Actions:	L-Histidine is an essential amino acid that binds to metal ions and may aid in the transport of copper. Histidine is widely present at the active sites of enzymes. It also has a role in binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.
Biochem/physiol Actions:	Precursor of histamine by action of histidine decarboxylase.
Features and Benefits:	• Can be used in Metabolomics and Biochemical research • High-quality compound suitable for multiple research applications
General description:	L-Histidine is a proteinogenic amino acid and an essential amino acid required for histamine production. This positively charged amino acid is vital for growth, tissue repair, myelin sheath maintenance, and histamine synthesis. Histamine plays critical roles in immunity, gastric secretion, and more. L-Histidine is essential for blood cell production and tissue protection against radiation and heavy metals. L-Histidine plays a role as a metabolite and also acts as a cofactor in enzyme protection during protein synthesis. It is an L-enantiomer of histidine and is necessary for histamine synthesis and human development. L-Histidine finds applications in cell culture, metabolomics and biochemical research.
Other Notes:	For additional information on our range of Biochemicals , please complete this form .
Packaging:	1 kg in poly bottle
Packaging:	10 mg in glass bottle
Packaging:	25, 100 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98.5-101.0%
mp	282 °C (dec.) (lit.)
Storage Temp.	room temp
UNSPSC	12352209

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