4-Hydroxyestrone
SIGMA/H6012 - ≥90% (HPLC)
Synonym: 1,3,5(10)
CAS Number: 3131-23-5
Empirical Formula (Hill Notation): C18H22O3
Molecular Weight: 286.37
MDL Number: MFCD00079358
Linear Formula: C18H22O3
Product Type: Chemical
| assay | ≥90% (HPLC) |
| form | powder |
| InChI | 1S/C18H22O3/c1-18-9-8-11- |
| InChI key | XQZVQQZZOVBNLU-QDTBLXIISA |
| Quality Level | 100 ![]() |
| shipped in | ambient |
| SMILES string | [H][C@]12CC[C@]3(C)C(=O)C |
| solubility | methanol: 10 mg/mL, clear, colorless to faintly brownish-yellow |
| sterility | non-sterile |
| storage temp. | −20°C |
| Biochem/physiol Actions: | 4-Hydroxyestrone is an endogenous estrogen metabolite, which exhibits a strong neuroprotective effect against oxidative damage. It also provides effective protection against kanic acid-induced hippocampal oxidative damage in rats when compared to 17β-estradiol. 4-Hydroxyestrone regulates the angiogenic process during corpus luteum formation. It might be involved in an increased risk of cancer. 4-Hydroxyestrone is found in the early and mid-luteal phases. |
| Packaging: | 5, 25 mg in glass insert |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 199.9 °F - closed cup |
| Flash Point(C) | 93.3 °C - closed cup |
| Purity | ≥90% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |

