22(S)-Hydroxycholesterol

SIGMA/H5884

Synonym: 22β-Hydroxycholesterol; 5-Cholestene-3β,22(S)-diol

CAS Number: 22348-64-7
Empirical Formula (Hill Notation): C₂₇H₄₆O₂
Molecular Weight: 402.65
MDL Number: MFCD00010476
Linear Formula: C₂₇H₄₆O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-H5884-5MG	5 mg	$210.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (TLC)
form	powder
InChI	1S/C27H46O2/c1-17(2)6-11-25(29)18(3)22-9-10-23-21-8-7-19-16-20(28)12-14-26(19,4)24(21)13-15-27(22,23)5/h7,17-18,20-25,28-29H,6,8-16H2,1-5H3/t18-,20-,21-,22+,23-,24-,25-,26-,27+/m0/s1
InChI key	RZPAXNJLEKLXNO-QUOSNDFLSA-N
Quality Level	200
shipped in	ambient
SMILES string	[H][C@@]12[C@]([C@](CC[C@H](O)C3)(C)C3=CC2)([H])CC[C@@]4(C)[C@@]1([H])CC[C@]4([H])[C@]([H])(C)[C@@H](O)CCC(C)C
storage temp.	room temp

Application:	Human hepatoma cells were treated with 22(S)-Hydroxycholesterol to study cholesterol modulation by liver X receptor-mediated gene regulation.
Biochem/physiol Actions:	22(S)-Hydroxycholesterol modulates the lipid and glucose metabolism by acting on liver X receptors. It has the potential to reduce lipogenesis and the accumulation of lipid in hepatocytes, myotubes and non-adipose tissue.
Packaging:	10 mg in poly bottle
Packaging:	5 mg in glass bottle
Preparation Note:	22(S)-Hydroxycholesterol yields clear, colorless solution in chloroform at 20 mg/ml.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (TLC)
Storage Temp.	room temp
UNSPSC	12352211

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