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20-Hydroxyecdysone

SIGMA/H5142 - ≥93% (HPLC), powder

Synonym: β-Ecdysone; 2β,3β,14α,20β,22,25-Hexahydroxy-7-cholesten-6-one; Ecdysterone; Insect moulting hormone; Polypodine A

CAS Number: 5289-74-7
Empirical Formula (Hill Notation): C27H44O7
Molecular Weight: 480.63
MDL Number: MFCD00036740
Linear Formula: C27H44O7
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-H5142-5MG 5 mg
 $202.00
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45-H5142-10MG 10 mg
 $385.00
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45-H5142-25MG 25 mg
 $836.00
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application(s) agriculture
environmental
assay ≥93% (HPLC)
color white to off-white
form powder
InChI 1S/C27H44O7/c1-23(2,32)9-8-22(31)26(5,33)21-7-11-27(34)16-12-18(28)17-13-19(29)20(30)14-24(17,3)15(16)6-10-25(21,27)4/h12,15,17,19-22,29-34H,6-11,13-14H2,1-5H3/t15-,17-,19+,20-,21-,22+,24+,25+,26+,27+/m0/s1
InChI key NKDFYOWSKOHCCO-YPVLXUMRSA-N
Quality Level 100 
shipped in ambient
SMILES string [H][C@]12CC[C@]3(C)[C@H](CC[C@@]3(O)C1=CC(=O)[C@]4([H])C[C@@H](O)[C@@H](O)C[C@]24C)[C@@](C)(O)[C@H](O)CCC(C)(C)O
solubility alcohol: soluble
sterility non-sterile
storage temp. −20°C
Application: 20-Hydroxyecdysone has been used:
• in Leibovitz′s dissecting medium for culturing sorting zone and neuropil-associated glia and antennal lobes of Manduca sexta
• in Schneider′s medium to reproduce ex-vivo imaginal disc eversion
• as a supplement in Mcl8 medium for culturing Drosophila wing imaginal discs
Biochem/physiol Actions: 20-Hydroxyecdysone is an ecdysteroid hormone that plays a key role in insect development, cell proliferaton, growth and apoptosis by controlling gene expression involved in molting and metamorphosis. It acts through a heterodimeric receptor comprising the ecdysone receptor and the ultraspiracle proteins (USP).
Packaging: 10, 25 mg in poly bottle
Packaging: 5 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥93% (HPLC)
Storage Temp. −20°C
UNSPSC 12352200

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