L-Histidine monohydrochloride monohydrate
SIGMA/H4036
Synonym: L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
CAS Number: 5934-29-2
Empirical Formula (Hill Notation): C6H9N3O2 · HCl · H2O
Molecular Weight: 209.63
MDL Number: MFCD00151027
Linear Formula: C6H9N3O2 · HCl · H2O
Product Type: Chemical
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| application(s) | pharmaceutical (small molecule) |
| assay | ≥98.5% |
| biological source | non-animal source |
| foreign activity | cytotoxicity, tested |
| form | powder |
| impurities | endotoxin, heavy metals, residual solvents, tested |
| InChI | 1S/C6H9N3O2.ClH.H2O/c7-5( |
| InChI key | CMXXUDSWGMGYLZ-XRIGFGBMSA |
| manufacturer/tradename | Ajinomoto |
| mp | 254 °C (dec.) (lit.) |
| Quality Level | 400  |
| SMILES string | O.Cl.N[C@@H](Cc1c[nH]cn1) |
| solubility | H2O: 50 mg/mL |
| technique(s) | cell culture | mammalian: suitable |
| Application: | L-Histidine, an essential amino acid. It is used as a cell culture media component in the commercial biomanufacture of therapeutic recombinant proteins and monoclonal antibodies. L-Histidine monohydrochloride monohydrate is a modified version of L-Histidine with improved solubility. |
| General description: | Our SAFC® portfolio of high-quality raw materials for use in biopharmaceutical processing withstands strict quality control procedures plus the documentation and expertise to help our customers meet requirements as defined by the M-Clarity Program. M-Clarity Program Our comprehensive portfolio of upstream process chemicals not only provides biopharmaceutical manufacturers with high-quality raw materials for production of classical and novel therapies, but also helps them get to market faster and simplify regulatory challenges. Trust us to deliver supply chain transparency and reliable sourcing around the globe, streamlining your product qualification with best-in-class regulatory support and service. |
| General description: | To request documentation for this product, please contact Customer Support and select ‘Product Documentation’. Please note that access to the documentation for this product requires a confidentiality disclosure agreement. |
| Legal Information: | SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.5% |
| mp | 254 °C (dec.) (lit.) |
| UNSPSC | 12352209 |