HiTrap® Capto™ Core 700
SIGMA/GE17-5481-51 - Cytiva 17-5481-51, pack of 5 × 1 mL
Synonym: Capto Core 700 Column; FPLC column; binding column; chromatography column; multimodal resin; size exclusion column; virus polishing resin
Product Type: Chemical
HiTrap Capto Core 700
| avg. part. size | 75 (d₅₀v is the median particle size of the cumulative volume distribution) |
| capacity | ~13 mg binding capacity (ovalbumin) |
| cleaning | 3-14(pH interval where the medium can be subjected to, for cleaning- or sanitization-in-place.) |
| column I.D. | 7 mm |
| ligand | octylamine |
| manufacturer/tradename | Cytiva 17-5481-51 |
| matrix | highly cross-linked agarose |
| packaging | pack of 5 × 1 mL |
| parameter | 5 bar |
| suitability | suitable for bioprocess medium |
| working range | 2-14(pH interval where the medium can be operated without significant change in function.) |
| Analysis Note: | To view the Certificate of Analysis for this product, please visit www.cytiva.com   . |
| Features and Benefits: | • High capacity and productivity in flowthrough mode. • Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification. • Wide operational window of pH and conductivity. |
| General description: | Dynamic binding capacities were measured at 10% breakthrough with a residence time of 3 min (1.6 ml/min = 200 cm/h) in HiScreen columns. Buffer: 20 mM Tris-HCl, 150 mM NaCl, pH 7.5. |
| General description: | HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess resin for intermediate purification and polishing of viruses and other large biomolecules. Capto Core 700 is a novel, layered bead chromatography resin consisting of a porous outer layer and ligand-activated core. The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged. These internalized ligands bind impurities strongly over a wide range of pH and salt concentration. The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured. |
| Legal Information: | Capto is a trademark of Cytiva |
| Legal Information: | HiTrap is a registered trademark of Cytiva |
| Preparation Note: | Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service. |
| Preparation Note: | Store at 4 to 30 °C (20% Ethanol) |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501 |
| RIDADR | UN1170 - class 3 - PG 3 - Ethanol, solution |
| UNSPSC | 23151817 |