SP Sepharose™ XL
SIGMA/GE17-5073-01 - Cytiva 17-5073-01, pack of 300 mL
Synonym: Cation Exchange Resin; SP Sepharose XL
Product Type: Chemical
| average diameter | 90 μm |
| cleaning in place | 3-14 |
| description | Ion Exchanger Type (value) |
| ligand | sulphopropyl |
| manufacturer/tradename | Cytiva 17-5073-01 |
| matrix | 6% cross-linked agarose with dextran surface extenders |
| packaging | pack of 300 mL |
| particle size | 45-165 μm |
| suitability | suitable for bioprocess medium |
| working range | 4-13 |
| Analysis Note: | To view the Certificate of Analysis for this product, please visit www.cytiva.com   . |
| Application: | SP Sepharose™ XL is based on a highly cross-linked, bead formed 6% Agarose matrix similar to the well established SP Sepharose™ Fast FLow media. Dextran chains are covalently coupled to the Agarose matrix and modified with sulphopropyl (SP) strong cation exchange groups through chemically stable ether bonds. The stable Agarose matrix and long, flexible chains of Dextran with bound charged groups work together to increase loading capacity whilst allowing high flow rates With its high loading capacities and excellent physical and chemical stability, SP Sepharose™ XL is suitable for the capture stage of a downstream process, which is characterised by large loads of crude samples. As member of the BioProcess media range, SP Sepharose™ XL meets industrial demands with security of supply and comprehensive technical and regulatory support. |
| Features and Benefits: | • High loading capacities give more productive capture from clarified feedstocks. • Strong cation exchanger designed for capture steps • High chemical stability for effective CIP/sanitization • The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool. |
| General description: | SP Sepharose™ XL is a strong cation exchanger designed for use in the capture steps of biomolecules from clarified feed-stocks. |
| Legal Information: | Sepharose is a trademark of Cytiva |
| Preparation Note: | Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service. |
| Preparation Note: | Store at 4 to 30 °C (20% Ethanol + 0.2 M Sodium Acetate) |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501 |
| RIDADR | NONH for all modes of transport |
| UNSPSC | 41106500 |