Anx Sepharose™ Fast Flow High Sub
SIGMA/GE17-1287-10 - Cytiva 17-1287-10, pack of 25 mL
Synonym: ANX Sepharose 4 FF; IEX resin; chromatography resin; gel; ion exchange resin; matrix; weak anion resin
Product Type: Chemical
| average diameter | 90 μm |
| cleaning in place | 2-14 |
| description | Ion Exchanger Type (value) |
| ligand | diethylaminopropyl |
| manufacturer/tradename | Cytiva 17-1287-10 |
| matrix | 4% cross-linked agarose |
| packaging | pack of 25 mL |
| particle size | 45-165 μm |
| suitability | suitable for bioprocess medium |
| working range | 3-13 |
| Analysis Note: | To view the Certificate of Analysis for this product, please visit www.cytiva.com   . |
| Application: | ANX Sepharose™ Fast FLow (high sub) is part of the Sepharose™ Fast FLow ion exchange platform, which has been the industrial standard for ion exchange chromatography during recent decades. ANX Sepharose™ 4 Fast FLow (high sub) is a weak anion exchanger medium with tertiary amine groups attached to the base matrix Sepharose™ 4 Fast FLow via ether linkage and a hydrophilic spacer arm. The diethylaminopropylgroup is coupled in a mode that precludes formation of quaternary groups, which are typically seen on traditional DEAE media, resulting in a truly weak anion exchanger. The base matrix, Sepharose™ 4 Fast Flow, is a highly cross-linked, 4% Agarose derivative with high chemical and physical stability and broad separation range. ANX Sepharose™ 4 Fast FLow (high sub) has high chemical stability, allowing well proven cleaning-in-place (CIP) and sanitization protocols. As member of the BioProcess media range, ANX Sepharose™ 4 Fast FLow (high sub) meets industrial demands with security of supply and comprehensive technical and regulatory support. |
| Features and Benefits: | • Weak anion exchanger with different selectivity compared with traditional ion exchangers. • Applicable for separation of high molecular weight Proteins • Developed in co-operation with leading large-scale pharmaceutical manufacturers • High chemical stability allows for well proven CIP and sanitization protocols • The hydrophilic nature of the base matrix ensures Low levels of non-specific binding leading to Low levels of host cell-derived impurities in the elution pool. |
| General description: | ANX Sepharose™ 4 Fast FLow (high sub) is a weak anion exchanger, with a different selectivity compared with traditional ion exchangers. It is optimized for the separation of larger proteins. |
| Legal Information: | Sepharose is a trademark of Cytiva |
| Preparation Note: | Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service. |
| Preparation Note: | Store at 4 to 30 °C (20% Ethanol) |
| Symbol |  GHS02 |
| Signal word | Warning |
| Hazard statements | H226 |
| Precautionary statements | P210 - P235 - P241 - P280 - P303 + P361 + P353 - P501 |
| RIDADR | NONH for all modes of transport |
| UNSPSC | 47101511 |