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Guanosine 5′-[β-thio]diphosphate trilithium salt

SIGMA/G7637 - ≥85% (HPLC), powder

Synonym: GDPβS trilithium salt; GDP-β-S; GDP-β-S-Li3

CAS Number: 97952-36-8
Empirical Formula (Hill Notation): C10H12Li3N5O10P2S
Molecular Weight: 477.07
MDL Number: MFCD00057735
Linear Formula: C10H12Li3N5O10P2S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G7637-5MG 5 mg
 $182.00
1/EA		 Add To Favorites
45-G7637-25MG 25 mg
 $603.00
1/EA		 Add To Favorites

 

assay ≥85% (HPLC)
color white
form powder
InChI 1S/C10H15N5O10P2S.3Li/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(24-9)1-23-26(19,20)25-27(21,22)28;;;/h2-3,5-6,9,16-17H,1H2,(H,19,20)(H2,21,22,28)(H3,11,13,14,18);;;/q;3*+1/p-3/t3-,5-,6-,9-;;;/m1.../s1
InChI key LMCWQGPJYZRMKU-CYCLDIHTSA-K
Quality Level 200 
shipped in dry ice
SMILES string [Li+].[Li+].[Li+].NC1=Nc2c(ncn2[C@@H]3O[C@H](COP([O-])(=O)OP([O-])([O-])=S)[C@@H](O)[C@H]3O)C(=O)N1
solubility H2O: 20 mg/mL (Solutions are very unstable; prepare immediately prior to use.)
storage temp. −20°C
Application: Guanosine 5′-[β-thio]diphosphate trilithium salt has been used as an inhibitor of G-protein activation to study its effects on acetylcholine current in bag cell neurons. It has also been used to study its effects on cholinergic-dependent plateau potentials.
Biochem/physiol Actions: Guanosine 5′-[β-thio]diphosphate is a non-hydrolyzable analog of guanosine. It functions as an inhibitor of G-protein activation.
Features and Benefits: This compound is a featured product for Cyclic Nucleotide research. Click here  to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Other Notes: Non-hydrolyzable GDP analog
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥85% (HPLC)
Storage Temp. −20°C
UNSPSC 41106305

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