Glycine

SIGMA/G7126 - ReagentPlus^®, ≥99% (HPLC)

Synonym: Aminoacetic acid; Aminoethanoic acid; Glycocoll

CAS Number: 56-40-6
Empirical Formula (Hill Notation): C₂H₅NO₂
Molecular Weight: 75.07
EC Number: 200-272-2
MDL Number: MFCD00008131; MFCD00008131
Linear Formula: NH₂CH₂COOH
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-G7126-10MG	10 mg	$31.70 1/EA	Add To Favorites
45-G7126-100G	100 g	$42.20 1/EA	Add To Favorites
45-G7126-500G	500 g	$71.20 1/EA	Add To Favorites
45-G7126-1KG	1 kg	$119.00 1/EA	Add To Favorites
45-G7126-5KG	5 kg	$447.00 1/EA	Add To Favorites
45-G7126-25KG	25 kg	$1600.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: G7126-100G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99% (HPLC)
cation traces	≤0.01% (Ammonia (NH3))
color	white to off-white
form	powder
functional group	amine
	carboxylic acid
impurities	≤0.01% Ammonia
InChI	1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChI key	DHMQDGOQFOQNFH-UHFFFAOYSA-N
loss	≤0.2% loss on drying
mp	240 °C (dec.) (lit.)
pKa (25 °C)	(1) 2.35, (2) 9.60
	2.35
product line	ReagentPlus^®
Quality Level	200
SMILES string	NCC(O)=O
solubility	H₂O: 200 mg/mL, clear, colorless to faintly yellow
storage temp.	room temp
technique(s)	western blot: suitable

Application:	• Glycine has been added in the transfer buffer during western blotting procedure. • It has been used in the solution prepared for dissolving formazan crystals in the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyltetrazolium bromide) cytotoxicity assay. • It has been used for terminating the rat basophilic leukemia (RBL) assay.
Biochem/physiol Actions:	Glycine is an inhibitory neurotransmitter in the central nervous system and works as an allosteric regulator of NMDA (N-methyl-D-aspartate) receptors. It is involved in processing of motor and sensory data, thereby regulating movement, vision and audition.
Biochem/physiol Actions:	Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Features and Benefits:	• Suitable for Cell Biology and Biochemical research • High-quality compound suitable for multiple research applications
General description:	Glycine is a non-chiral amino acid. Glycine is a molecule with pI of 6.7, which is similar to the pH of stacking region in polyacrylamide gels. It has advantage of low mobility, hydrophobicity and it does not associate with proteins.
General description:	Glycine is a proteinogenic amino acid that plays a diverse array of roles in biochemistry and physiology. This non-essential, non-polar glucogenic amino acid acts as an inhibitory neurotransmitter in the central nervous system, but also works alongside glutamate as a co-agonist at NMDA receptors. As a precursor, glycine serves as a building block for various macromolecules, playing a crucial role in cellular processes. Beyond its vital biological functions, glycine demonstrates remarkable versatility in various research applications. Its application as a biochemical reagent makes it invaluable in numerous assays and procedures. Its buffering capacity allows it to play a critical role in protein analysis techniques like SDS-PAGE and Western Blotting, chromatography, and cell culture. Glycine′s zwitterionic nature makes it an effective buffer across a range of pH values. In immunology research, it is widely used in the preparation of buffers for Western Blotting and other techniques. Additionally, its compatibility with various enzymes makes it useful in enzymatic assays like lactate determination. Furthermore, glycine contributes to the formulation of buffers for protein stabilization, pH control, and enzymatic reactions.
Legal Information:	ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany
Other Notes:	For additional information on our range of Biochemicals , please complete this form .
Packaging:	1 kg in poly bottle
Packaging:	10 mg in glass bottle
Packaging:	100, 500 g in poly bottle
Packaging:	5, 25 kg in poly drum

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99% (HPLC)
mp	240 °C (dec.) (lit.)
Storage Temp.	room temp
UNSPSC	12352209

To Order From a Quote