Guanosine

SIGMA/G6752 - ≥98%

Synonym: 9-(β-D-Ribofuranosyl)guanine; Guanine-9-β-D-ribofuranoside

CAS Number: 118-00-3
Empirical Formula (Hill Notation): C₁₀H₁₃N₅O₅
Molecular Weight: 283.24
EC Number: 204-227-8
MDL Number: MFCD00010182
Linear Formula: C₁₀H₁₃N₅O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-G6752-1G	1 g	$68.60 1/EA	Add To Favorites
45-G6752-25G	25 g	$84.70 1/EA	Add To Favorites
45-G6752-100G	100 g	$254.00 1/EA	Add To Favorites
45-G6752-500G	500 g	$1030.00 1/EA	Add To Favorites

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This image depicts SKU: G6752-25G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
biological source	microbial
form	powder
InChI	1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1
InChI key	NYHBQMYGNKIUIF-UUOKFMHZSA-N
mp	250 °C (dec.) (lit.)
Quality Level	200
SMILES string	[H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1
solubility	formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

Application:	Guanosine has been used: • as a reference standard for the analysis of glucosinolates by high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS) • as a component of Mouse Embryonic Fibroblasts (MEFs) culture • as a standard for the detection of residual RNA contaminant in oil palm plant genome samples by HPLC
Biochem/physiol Actions:	Guanosine nucleoside elicits cellular effect as the guanine-based purinergic system. It modulates glutamate uptake by glutamate transporters. It may have neuroprotective functionality in central nervous system disorders. Guanosine promotes neurite arborization, outgrowth, proliferation and differentiation. Administration of guanosine replenished GTP and elicits protective function in renal ischemic injury.
General description:	Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid, intestinal cells, blood-brain barrier and in brain microvessels.
Packaging:	1, 25, 100, 500 g in poly bottle

Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3

Purity	≥98%
mp	250 °C (dec.) (lit.)
UNSPSC	41106305

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