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Gemcitabine hydrochloride

SIGMA/G6423 - ≥98% (HPLC)

Synonym: 2′-Deoxy-2′,2′-difluorocytidine; dFdC; Gemzar (Lilly); LY-188011; dFdC; dFdCyd

CAS Number: 122111-03-9
Empirical Formula (Hill Notation): C9H11F2N3O4 · HCl
Molecular Weight: 299.66
MDL Number: MFCD01735988
Linear Formula: C9H11F2N3O4 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G6423-10MG 10 mg
 $81.70
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45-G6423-50MG 50 mg
 $322.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6423-10MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6423-50MG

 

assay ≥98% (HPLC)
form powder
InChI 1S/C9H11F2N3O4.ClH/c10-9(11)6(16)4(3-15)18-7(9)14-2-1-5(12)13-8(14)17;/h1-2,4,6-7,15-16H,3H2,(H2,12,13,17);1H/t4-,6-,7-;/m1./s1
InChI key OKKDEIYWILRZIA-OSZBKLCCSA-N
originator Eli Lilly
Quality Level 100 
SMILES string Cl.NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](CO)[C@@H](O)C2(F)F
solubility H2O: ≥10 mg/mL
storage condition desiccated
  protect from light
storage temp. room temp
Application: Gemcitabinehydrochloride has been used as a chemotherapeutic agent to study its effects onthe human pancreatic adenocarcinoma cell lineIt has been used as a chemotherapeutic to study its resistance inpancreatic stellate cells (PSCs)It has also been used to study its effects on patient-derivedxenograft (PDX) organoids.
Biochem/physiol Actions: Gemcitabine is a widely used antineoplastic agent and antimetabolite.
Biochem/physiol Actions: Gemcitabine is a widely used antitumor agents in both clinics and research labs. It is an antineoplastic agent and antimetabolite.
Features and Benefits: This compound is a featured product for Apoptosis research. Click here  to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
General description: Gemcitabineis a pyrimidine nucleoside analog of deoxycytidine. It exhibits anticancereffects against various cancers.
Packaging: 10, 50 mg in glass bottle
Symbol GHS08  GHS08
Signal word Danger
Hazard statements H360
Precautionary statements P201 - P308 + P313
Hazard Codes Xn
Risk Statements 63-62
Safety Statements 53-36/37
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 12352200

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