Guanosine
SIGMA/G6264 - BioReagent, suitable for cell culture
Synonym: 9-(β-D-Ribofuranosyl)guanine; Guanine-9-β-D-ribofuranoside
CAS Number: 118-00-3
Empirical Formula (Hill Notation): C10H13N5O5
Molecular Weight: 283.24
EC Number: 204-227-8
MDL Number: MFCD00010182
Linear Formula: C10H13N5O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6264-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6264-5G
| assay | ≥98% |
| biological source | synthetic |
| form | powder |
| InChI | 1S/C10H13N5O5/c11-10-13-7 |
| InChI key | NYHBQMYGNKIUIF-UUOKFMHZSA |
| mp | 250 °C (dec.) (lit.) |
| product line | BioReagent |
| Quality Level | 200  |
| shipped in | ambient |
| SMILES string | [H]O[H].NC1=Nc2c(ncn2[C@@ |
| solubility | 0.05 M acetic acid: 1 mg/mL, clear, colorless |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| Application: | Guanosine has been used: • as a ribonucleoside component of the basal medium to study its effects on Bacillus mojavensis′s anaerobic growth • as a component of the Dulbecco′s modified Eagle medium (DMEM) to culture mouse-derived embryonic stem cells • as a component of the nucleoside solution to culture chicken embryonic stem cells |
| Biochem/physiol Actions: | Guanosine is a purine nucleoside that exhibits important functions in cell metabolism. It has also shown neuroprotective and neurotrophic effects in glial cells, hippocampal neurons, and pheochromocytoma cells by inducing proliferation and differentiation and also exerting anti-apoptotic effects. Guanosine acts as a therapeutic agent against several neuropathologies. It exerts its effects against sepsis-induced cognitive impairment, hepatic encephalopathy, lipopolysaccharide (LPS)-induced inflammation, ischemic injury, and azide-induced oxidative damage. Guanosine is suitable for use in cell culture applications as a precursor of guanosine monophosphate (GMP), guanosine diphosphate (GDP), guanosine triphosphate (GTP), and cyclic GMP (cGMP). |
| Packaging: | 1, 5 g in poly bottle |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Purity | ≥98% |
| mp | 250 °C (dec.) (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12352205 |