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G 418 disulfate salt

SIGMA/G1279 - suitable for plant cell culture, BioReagent

Synonym: Antibiotic G418

CAS Number: 108321-42-2
Empirical Formula (Hill Notation): C20H40N4O10 · 2H2SO4
Molecular Weight: 692.71
MDL Number: MFCD00058314
Linear Formula: C20H40N4O10 · 2H2SO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G1279-1G 1 g
 $387.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G1279-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G1279-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G1279-5G

 

antibiotic activity spectrum Gram-negative bacteria
application(s) agriculture
color white to off-white
form powder
InChI 1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1
InChI key UHEPSJJJMTWUCP-NKCAIAFTSA-N
mode of action protein synthesis | interferes
potency ≥720 μg per mg (Dried basis)
product line BioReagent
Quality Level 200 
SMILES string OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O
solubility 100 mg/mL (H2O clear)
storage temp. 2-8°C
technique(s) cell culture | plant: suitable
Application: G418 disulfate salt is an aminoglycoside antibiotic similar in structure to gentamicin used for selection and maintenance of prokaryotic and eukaryotic cells transfected with a iNOS promoter construct and neomycin resistance gene†. Optimal concentrations for selection and maintenance vary by cell lines. Bacteria and algae require 5 μg/mL or less while animal cells may require 300-500 μg/mL.
Disclaimer: The product is stable for three years when stored at 2-8°C.
General description: Chemical structure: aminoglycoside
Packaging: 1, 5 g in glass bottle
Packaging: 250 mg in glass bottle
Preparation Note: G418 powder is soluble in water at 100 mg/mL.
Storage Temp. 2-8°C
UNSPSC 10171502

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