L-Glutamic acid
SIGMA/G1251 - ReagentPlus®, ≥99% (HPLC)
Synonym: (S)-2-Aminopentanedioic acid; Glu
CAS Number: 56-86-0
Empirical Formula (Hill Notation): C5H9NO4
Molecular Weight: 147.13
EC Number: 200-293-7
MDL Number: MFCD00002634
Linear Formula: HO2CCH2CH2CH(NH2)CO2H
Product Type: Chemical
| agency | suitable for SM 5210 |
| assay | ≥99% (HPLC) |
| cation traces | C: 40.4-41.2% |
| N: 9.2-9.8% | |
| color | white to off-white |
| density | 1.54 g/cm3 at 20 °C |
| form | powder |
| InChI | 1S/C5H9NO4/c6-3(5(9)10)1- |
| InChI key | WHUUTDBJXJRKMK-VKHMYHEASA |
| mp | 205 °C (dec.) (lit.) |
| product line | ReagentPlus® |
| Quality Level | 200 ![]() |
| SMILES string | N[C@@H](CCC(O)=O)C(O)=O |
| solubility | 1 M HCl: soluble 100 mg/mL |
| technique(s) | microbiological culture: suitable |
| Application: | L-Glutamic acid has been used to enhance endogenous acetylcholine overflow. It has been used as a supplement in the growth medium of meat-Spoiling Pseudomonas fragi 72. |
| Biochem/physiol Actions: | An excitatory amino acid neurotransmitter that is an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). |
| Biochem/physiol Actions: | Glutamic acid, or glutamate, the salt form of glutamic acid, functions as a neurotransmitter and also serves as a precursor to other neurotransmitters such as γ-aminobutyric acid. Glutamic acid also plays a key role in many metabolic pathways, that controls growth, reproduction, maintenance and immunity. It is converted to α-ketoglutarate, a key component of the TCA (tricarboxylic acid) cycle, and a precursor for the biosynthesis of nucleic acids and certain amino acids. In cells, glutamine is converted to glutamate by the enzyme glutaminase. Glutamine serves as a source of energy for rapidly dividing cells comprising lymphocytes, enterocytes, macrophages and tumors. Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signaling. It is also known to be associated with the inhibition of apoptosis. |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 100, 500 g in poly bottle |
| Packaging: | 5 kg in poly drum |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% (HPLC) |
| mp | 205 °C (dec.) (lit.) |
| Density | 1.54 g/cm3 at 20 °C |
| UNSPSC | 12352209 |

