γ-Glu-Cys
SIGMA/G0903 - ≥80% (HPLC)
Synonym: γ-L-Glutamyl-L-cysteine; des-Gly-glutathione reduced form
CAS Number: 636-58-8
Empirical Formula (Hill Notation): C8H14N2O5S
Molecular Weight: 250.27
MDL Number: MFCD00237863
Linear Formula: C8H14N2O5S
Product Type: Chemical
| assay | ≥80% (HPLC) |
| color | white to off-white |
| composition | Peptide content, ≥60% elemental analysis |
| form | powder |
| InChI | 1S/C8H14N2O5S/c9-4(7(12)1 |
| InChI key | RITKHVBHSGLULN-WHFBIAKZSA |
| Quality Level | 200 ![]() |
| SMILES string | N[C@@H](CCC(=O)N[C@@H](CS |
| storage temp. | −20°C |
| technique(s) | ligand binding assay: suitable |
| Amino Acid Sequence: | Glu-Cys |
| Application: | γ-Glu-Cys is used to study the active sites and kinetics of glutathione synthetase(s). It has also been used for the extraction and quantification of low molecular weight thiols from Arabidopsis tissues. |
| Biochem/physiol Actions: | γ-L-Glutamyl-L-cysteine (γ-Glu-Cys) is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s). γ-Glu-Cys is generated by the cleavage of the Cys-Gly peptide bond of glutathione. It is also essential for the formation of phytochelatins, which are cysteine-rich thiol-reactive peptides. |
| Physical form: | Lyophilized from 0.1% TFA. |
| Symbol | GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥80% (HPLC) |
| Storage Temp. | −20°C |
| UNSPSC | 12352209 |


