γ-Glu-Cys

SIGMA/G0903 - ≥80% (HPLC)

Synonym: γ-L-Glutamyl-L-cysteine; des-Gly-glutathione reduced form

CAS Number: 636-58-8
Empirical Formula (Hill Notation): C₈H₁₄N₂O₅S
Molecular Weight: 250.27
MDL Number: MFCD00237863
Linear Formula: C₈H₁₄N₂O₅S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-G0903-25MG	25 mg	$128.00 1/EA		Add To Favorites
45-G0903-100MG	100 mg	$420.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥80% (HPLC)
color	white to off-white
composition	Peptide content, ≥60% elemental analysis
form	powder
InChI	1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1
InChI key	RITKHVBHSGLULN-WHFBIAKZSA-N
Quality Level	200
SMILES string	N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O
storage temp.	−20°C
technique(s)	ligand binding assay: suitable

Amino Acid Sequence:	Glu-Cys
Application:	γ-Glu-Cys is used to study the active sites and kinetics of glutathione synthetase(s). It has also been used for the extraction and quantification of low molecular weight thiols from Arabidopsis tissues.
Biochem/physiol Actions:	γ-L-Glutamyl-L-cysteine (γ-Glu-Cys) is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s). γ-Glu-Cys is generated by the cleavage of the Cys-Gly peptide bond of glutathione. It is also essential for the formation of phytochelatins, which are cysteine-rich thiol-reactive peptides.
Physical form:	Lyophilized from 0.1% TFA.

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥80% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352209

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