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γ-Glu-Cys

SIGMA/G0903 - ≥80% (HPLC)

Synonym: γ-L-Glutamyl-L-cysteine; des-Gly-glutathione reduced form

CAS Number: 636-58-8
Empirical Formula (Hill Notation): C8H14N2O5S
Molecular Weight: 250.27
MDL Number: MFCD00237863
Linear Formula: C8H14N2O5S
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-G0903-25MG 25 mg
$121.00
1/EA
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45-G0903-100MG 100 mg
$398.00
1/EA
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assay ≥80% (HPLC)
color white to off-white
composition Peptide content, ≥60% elemental analysis
form powder
InChI 1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1
InChI key RITKHVBHSGLULN-WHFBIAKZSA-N
Quality Level 200 
SMILES string N[C@@H](CCC(=O)N[C@@H](CS)C(O)=O)C(O)=O
storage temp. −20°C
technique(s) ligand binding assay: suitable
Amino Acid Sequence: Glu-Cys
Application: γ-Glu-Cys is used to study the active sites and kinetics of glutathione synthetase(s). It has also been used for the extraction and quantification of low molecular weight thiols from Arabidopsis tissues.
Biochem/physiol Actions: γ-L-Glutamyl-L-cysteine (γ-Glu-Cys) is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s). γ-Glu-Cys is generated by the cleavage of the Cys-Gly peptide bond of glutathione. It is also essential for the formation of phytochelatins, which are cysteine-rich thiol-reactive peptides.
Physical form: Lyophilized from 0.1% TFA.
Purity ≥80% (HPLC)
Storage Temp. −20°C
UNSPSC 12352209

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