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GW2974

SIGMA/G0668 - ≥98% (HPLC), solid

Synonym: N4-(1-Benzyl-1H-indazol-5-yl)-N6,N6-dimethyl-pyrido­[3,4-d]­pyrimidine-4,6-diamine

CAS Number: 202272-68-2
Empirical Formula (Hill Notation): C23H21N7
Molecular Weight: 395.46
MDL Number: MFCD04974495
Linear Formula: C23H21N7
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-G0668-50MG 50 mg
 $264.00
1/EA		 Add To Favorites
45-G0668-250MG 250 mg
 $1010.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G0668-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G0668-50MG

 

assay ≥98% (HPLC)
color yellow
form solid
InChI 1S/C23H21N7/c1-29(2)22-11-19-20(13-24-22)25-15-26-23(19)28-18-8-9-21-17(10-18)12-27-30(21)14-16-6-4-3-5-7-16/h3-13,15H,14H2,1-2H3,(H,25,26,28)
InChI key DYYZXRCFCVDSKD-UHFFFAOYSA-N
originator GlaxoSmithKline
Quality Level 100 
SMILES string CN(C)c1cc2c(Nc3ccc4n(Cc5ccccc5)ncc4c3)ncnc2cn1
solubility DMSO: ≥20 mg/mL
Biochem/physiol Actions: Potent and selective dual inhibitor of EGFR (IC50 = 0.016 mM) and ErbB-2 receptor tyrosine kinase.
Features and Benefits: This compound is a featured product for Kinase Phosphatase Biology research. Click here  to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .
Features and Benefits: This compound was developed by GlaxoSmithKline . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Legal Information: Sold for research purposes under agreement from Glaxo­Smith­Kline
Packaging: 50, 250 mg in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98% (HPLC)
UNSPSC 51111800

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