Corosolic acid from Lagerstroemia speciosa

SIGMA/G0549 - ≥98% (HPLC)

Synonym: Corosolic acid; (2α,3β)-2,3-Dihydroxyurs-12-en-28-oic acid; 2α-Hydroxyursolic acid; Colosolic acid; Corsolic acid; Glucosol

CAS Number: 4547-24-4
Empirical Formula (Hill Notation): C₃₀H₄₈O₄
Molecular Weight: 472.70
MDL Number: MFCD06794973; MFCD06794973
Linear Formula: C₃₀H₄₈O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-G0549-10MG	10 mg	$394.00 1/EA	Add To Favorites
45-G0549-50MG	50 mg	$1190.00 1/EA	Add To Favorites

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This image depicts SKU: G0549-50MG

Properties
Descriptions
Safety Info.
Basic Data

application(s)	metabolomics vitamins, nutraceuticals, and natural products
assay	≥98% (HPLC)
form	powder
InChI	1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21+,22-,23+,24+,27+,28-,29-,30+/m1/s1
InChI key	HFGSQOYIOKBQOW-ZSDYHTTISA-N
Quality Level	200
SMILES string	O[C@H]1[C@H](O)C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(O)=O)[C@@]4([H])[C@@H](C)[C@H](C)CC5)([H])[C@]3(C)C1
solubility	methanol: 1 mg/mL, clear, colorless
storage temp.	2-8°C

Application:	Corosolic acid from Lagerstroemia speciosa has been used to study the inhibiting activity of ursolic acid and its derivative against colon cancer cells by causing degradation of β-catenins.
Biochem/physiol Actions:	Corosolic acid from Lagerstroemia speciose shows a variety of biological activities such as anti-proliferation, apoptosis, and anti-carcinogenic. It exhibits an inhibiting effect on the post-challenge plasma glucose levels in humans. Corosolic acid, due to its ability to improve glucose metabolism, has been touted to be used in the management of Type-2 Diabetes. It improves hypertension, oxidative stress, and inflammation, thereby being a potential candidate to be used against atherosclerosis-related diseases.
Biochem/physiol Actions:	Triterpene phytochemical found in medicinal herbal extracts. Possesses antiatherosclerotic, antihyperlipidemic, antioxidant, antiinflammatory, antifungal, antiviral and antineoplastic activities.
General description:	Corosolic acid from Lagerstroemia speciosa is a pentacyclic triterpenoid found in a variety of plants, such as apples, basil, bilberries, cranberries, and prunes. It is a natural derivative of ursolic acid.
Packaging:	10 mg in glass bottle
Packaging:	50 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	2-8°C
UNSPSC	12352106

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