Fluconazole
SIGMA/F8929 - ≥98% (HPLC), powder
Synonym: 2-
CAS Number: 86386-73-4
Empirical Formula (Hill Notation): C13H12F2N6O
Molecular Weight: 306.27
MDL Number: MFCD00274549
Linear Formula: C13H12F2N6O
Product Type: Chemical
| antibiotic activity spectrum | fungi |
| assay | ≥98% (HPLC) |
| form | powder |
| InChI | 1S/C13H12F2N6O/c14-10-1-2 |
| InChI key | RFHAOTPXVQNOHP-UHFFFAOYSA |
| mode of action | enzyme | inhibits |
| Quality Level | 100 ![]() |
| SMILES string | FC1=CC(F)=C(C(CN2N=CN=C2) |
| solubility | DMSO: 5 mg/mL |
| storage temp. | room temp |
| Application: | Fluconazole has been used to assess minimum inhibitory concentration (MIC)-fungal assay. It has also been used as a positive control in antifungal assay of plants. |
| Biochem/physiol Actions: | Fluconazole is an antifungal agent. It is highly selective inhibitor of fungal cytochrome P-450 sterol C-14 α-demethyllation. Fluconazole is a potent inhibitor of CYP2C9. Fluconazole interferes with fungal ergosterol synthesis and downregulates the metallothionein gene. |
| Biochem/physiol Actions: | Fluconazole is an antifungal agent; highly selctive inhibitor of fungal cytochrome P-450 sterol C-14 α-demethyllation. Potent inhibitor of CYP2C9. Interferes with fungal ergosterol synthesis; downregulates metallothionein gene. |
| Features and Benefits: | This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm . |
| General description: | Fluconazole is used to treat adult neutropenic patients with invasive candidiasis (IC). |
| Packaging: | 100 mg in glass bottle |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H360D - H412 |
| Precautionary statements | P201 - P202 - P264 - P273 - P301 + P312 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% (HPLC) |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |



