FR-900098 monosodium salt
SIGMA/F8307 - ≥97% (NMR)
Synonym: (3-
CAS Number: 73226-73-0
Empirical Formula (Hill Notation): C5H11NNaO5P
Molecular Weight: 219.11
MDL Number: MFCD17215926
Linear Formula: C5H11NNaO5P
Product Type: Chemical
| assay | ≥97% (NMR) |
| color | white to light brown |
| form | powder |
| InChI | 1S/C5H12NO5P.Na/c1-5(7)6( |
| InChI key | LCFXFDGYDKNWMD-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | [Na+].CC(=O)N(O)CCCP(O)([ |
| solubility | H2O: ≥20 mg/mL |
| storage condition | desiccated |
| protect from light | |
| storage temp. | −20°C |
| Biochem/physiol Actions: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice. |
| Biochem/physiol Actions: | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative. |
| Packaging: | 5, 25 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97% (NMR) |
| Storage Temp. | −20°C |
| UNSPSC | 51111800 |