Folic acid
SIGMA/F7876 - ≥97%
Synonym: PteGlu; Pteroyl-L-glutamic acid; Vitamin M
CAS Number: 59-30-3
Empirical Formula (Hill Notation): C19H19N7O6
Molecular Weight: 441.40
EC Number: 200-419-0
MDL Number: MFCD00079305
Linear Formula: C19H19N7O6
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F7876-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F7876-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F7876-10G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F7876-1G
| assay | ≥97% |
| biological source | synthetic (organic) |
| color | faint orange to dark orange-yellow |
| faint yellow to dark yellow | |
| form | powder |
| InChI | 1S/C19H19N7O6/c20-19-25-1 |
| InChI key | OVBPIULPVIDEAO-LBPRGKRZSA |
| mp | >285 °C |
| Quality Level | 200  |
| SMILES string | NC(N1)=NC(C2=C1N=CC(CNC3= |
| storage temp. | room temp |
| technique(s) | HPLC: suitable |
| Application: | Folic acid has been used: • to induce acute kidney injury in mice • as a supplement to cultivate MCF-7 breast cancer cells. • to construct folate or TNF-related apoptosis-including ligand (TRAIL)-conjugated nanomicelles |
| Biochem/physiol Actions: | Enzyme cofactor essential for the synthesis, methylation, and repair of DNA. Folic acid supplements may reduce colorectal cancer risk. |
| Biochem/physiol Actions: | Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics). |
| Packaging: | 1, 10, 25, 100 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Purity | ≥97% |
| mp | >285 °C |
| Storage Temp. | room temp |
| UNSPSC | 12352106 |