Fludrocortisone acetate

SIGMA/F6127 - ≥98%

Synonym: 9α-Fluoro-11β,17α,21-trihydroxy-4-pregnene-3,20-dione acetate; 9-Fluorocortisol acetate; 9-Fluorohydrocortisone acetate

CAS Number: 514-36-3
Empirical Formula (Hill Notation): C₂₃H₃₁FO₆
Molecular Weight: 422.49
EC Number: 208-180-4
MDL Number: MFCD00864160
Linear Formula: C₂₃H₃₁FO₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-F6127-1G	1 g	$105.00 1/EA	Add To Favorites
45-F6127-5G	5 g	$419.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98%
biological source	synthetic
form	powder
InChI	1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
InChI key	SYWHXTATXSMDSB-GSLJADNHSA-N
Quality Level	100
shipped in	ambient
SMILES string	CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
solubility	acetone: 50 mg/mL, clear, colorless to light yellow
sterility	non-sterile
storage temp.	room temp

Biochem/physiol Actions:	Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity.
General description:	Fludrocortisone acetate is secreted by adrenal cortex. It increases the reabsorption of sodium and secretion of potassium and hydrogen. Fludrocortisone is used to treat cerebral salt wasting syndrome and adrenal insufficiency. Fludrocortisone improves the sensitivity of blood vessels to catecholamines and increases the blood volume.

Symbol	GHS07,GHS08
Signal word	Warning
Hazard statements	H302 - H361
Precautionary statements	P201 - P301 + P312 + P330 - P308 + P313
Hazard Codes	Xn
Risk Statements	63
Safety Statements	22-26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98%
Storage Temp.	room temp
UNSPSC	12352200

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