Fenofibrate
SIGMA/F6020 - ≥99%, powder
Synonym: 2-
CAS Number: 49562-28-9
Empirical Formula (Hill Notation): C20H21ClO4
Molecular Weight: 360.83
EC Number: 256-376-3
MDL Number: MFCD00133314
Linear Formula: C20H21ClO4
Product Type: Chemical
| assay | ≥99% |
| color | off-white |
| form | powder |
| InChI | 1S/C20H21ClO4/c1-13(2)24- |
| InChI key | YMTINGFKWWXKFG-UHFFFAOYSA |
| originator | Abbott |
| Quality Level | 100  |
| SMILES string | CC(C)OC(=O)C(C)(C)Oc1ccc( |
| storage temp. | room temp |
| Application: | Fenofibrate has been used: • to study its effect on plasma lipids, liver phenotype and gene expression • to study its impact on endothelium-dependent vasodilatation of thoracic aorta • to administer to NASH knock-in mice along with a high fat diet (HFD) to study its effect |
| Biochem/physiol Actions: | Fenofibrate increases high density lipoprotein levels by reducing cholesteryl ester transfer protein expression. It is used in treating the condition of increased cholesterol levels in the blood, abnormal lipid levels in the body and also hypertriglyceridaemia. Fenofibrate is a lipid regulating drug and proliferator-activated receptor-α (PPARα) mediates its action. It decreases the plasma levels of fibrinogen and C-reactive protein. By this fenofibrate allows better flow-mediated dilatation and reduces the risk of atherosclerosis. Fenofibrate is also known to reduce uric acid levels. |
| Features and Benefits: | This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| Features and Benefits: | This compound was developed by Abbott . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Hazard statements | H412 |
| Precautionary statements | P273 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99% |
| Storage Temp. | room temp |
| UNSPSC | 12352200 |