p-Fluoro-DL-phenylalanine
SIGMA/F5251
Synonym: 4-
CAS Number: 51-65-0
Empirical Formula (Hill Notation): C9H10FNO2
Molecular Weight: 183.18
EC Number: 200-113-7
MDL Number: MFCD00002600
Linear Formula: FC6H4CH2CH(NH2)COOH
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | ≥98.0% (TLC) |
| color | white to off-white |
| form | powder |
| InChI | 1S/C9H10FNO2/c10-7-3-1-6( |
| InChI key | XWHHYOYVRVGJJY-UHFFFAOYSA |
| mp | 253-255 °C (dec.) (lit.) |
| Quality Level | 100 ![]() |
| SMILES string | NC(Cc1ccc(F)cc1)C(O)=O |
| Biochem/physiol Actions: | Inhibits mitosis and reversibly arrests HeLa cells in G2. |
| Biochem/physiol Actions: | p-Fluoro-DL-phenylalanine (pFPhe), a toxic antimetabolite, is a racemic mixture of a substituted (halogenated) benzoyl D and L phenylalanine useful as a selection marker for wine yeast transformation and with potential use in endomorphin, antiviral, and antimicrobial drug development. Phenylalanine analogue, rho-fluorophenylalanine (pFPhe) is also used to induce apoptosis. |
| Packaging: | 1, 5 g in poly bottle |
| Symbol | GHS06 |
| Signal word | Danger |
| Hazard statements | H300 |
| Precautionary statements | P264 - P301 + P310 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (TLC) |
| mp | 253-255 °C (dec.) (lit.) |
| UNSPSC | 12352209 |


