Flavin-Containing Monooxygenase-5, Microsomes human
SIGMA/F5178 - recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
Synonym: FMO-5
Product Type: Chemical
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| form | buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer) |
| mol wt | 55-60 kDa |
| packaging | vial of 2.5 mg |
| Quality Level | 200  |
| recombinant | expressed in baculovirus infected insect cells |
| shipped in | dry ice |
| specific activity | ≥700 units/mg protein |
| storage temp. | −70°C |
| UniProt accession no. | P49326  |
| Application: | FMO5 is the only FMO isoform expressed in both adult and fetal human liver. |
| Biochem/physiol Actions: | FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver. |
| Other Notes: | methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide. |
| Physical form: | Solution in 100 mM potassium phosphate buffer, pH 7.4. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥700 units/mg protein |
| Storage Temp. | −70°C |
| Enzyme Commission (EC) Number | 1.14.13.8 ( BRENDA | IUBMB ) |
| UNSPSC | 12352204 |