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5-Fluorouridine

SIGMA/F5130 - proapoptotic anitproliferative plant growth regulator

Synonym: 5-Fluorouracil 1β-D-ribofuranoside; FUrd

CAS Number: 316-46-1
Empirical Formula (Hill Notation): C9H11FN2O6
Molecular Weight: 262.19
EC Number: 206-260-3
MDL Number: MFCD00036832
Linear Formula: C9H11FN2O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F5130-100MG 100 mg
 $137.00
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45-F5130-250MG 250 mg
 $250.00
1/EA		 Add To Favorites
45-F5130-1G 1 g
 $752.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F5130-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F5130-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F5130-250MG

 

assay ≥99% (HPLC)
biological source synthetic (organic)
form powder
InChI 1S/C9H11FN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1
InChI key FHIDNBAQOFJWCA-UAKXSSHOSA-N
Quality Level 100 
SMILES string OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=C(F)C(=O)NC2=O
solubility water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
Application: 5-Fluorouridine has been used for labeling active transcription sites in the porcine fetal fibroblasts and human cell lines for immunocytochemistry analysis. It has also been used to monitor apoptosis during drug sensitivity assay in esophageal squamous cell carcinoma (ESCC) cells.
Biochem/physiol Actions: 5-Fluorouridine (FUrd) is cytotoxic towards cancer cells. FUrd is often used in chemical and biochemical comparison studies with fluorouracil and thymine analogs.
General description: 5-Fluorouridine (FUrd) is a fluoropyrimidine nucleoside analog and a cell-permeable modified RNA precursor.
Packaging: 1 g in poly bottle
Packaging: 100, 250 mg in poly bottle
Hazard Codes Xn
Risk Statements 68
Safety Statements 36/37
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99% (HPLC)
UNSPSC 41106305

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