Forskolin

SIGMA/F3917 - For use in molecular biology applications

Synonym: 7β-Acetoxy-8,13-epoxy-1α,6β,9α-trihydroxylabd-14-en-11-one; Coleonol; Colforsin

CAS Number: 66575-29-9
Empirical Formula (Hill Notation): C₂₂H₃₄O₇
Molecular Weight: 410.50
EC Number: 266-410-9
MDL Number: MFCD00082317
Linear Formula: C₂₂H₃₄O₇
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-F3917-10MG	10 mg	$322.00 1/EA	Add To Favorites
45-F3917-25MG	25 mg	$662.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (HPLC)
biological source	Coleus forskohlii
color	white to off-white
description	for activation of T cells
form	powder
InChI	1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1
InChI key	OHCQJHSOBUTRHG-KGGHGJDLSA-N
mol wt	410.50 g/mol
product line	BioReagent
Quality Level	200
SMILES string	CC(=O)O[C@H]1[C@@H](O)[C@H]2C(C)(C)CC[C@H](O)[C@]2(C)[C@@]3(O)C(=O)C[C@@](C)(O[C@]13C)C=C
solubility	ethanol: soluble
storage temp.	room temp
suitability	suitable for inhibits interleukin 2 (IL-2) production in Jurkat cells

Biochem/physiol Actions:	Cell-permeable diterpenoid that possesses anti-hypertensive, positive inotropic, and adenylyl cyclase activating properties. Many of its biological effects are due to its activation of adenylyl cyclase and the resulting increase in intracellular cAMP concentration. Forskolin effects calcium currents and inhibits MAP kinase.
General description:	Forskolin is a cell permeable diterpenoid isolated from Coleus forskohlii.
Packaging:	10, 25 mg in poly bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H312
Precautionary statements	P280 - P302 + P352 + P312 - P362 + P364 - P501
Hazard Codes	Xn
Risk Statements	21
Safety Statements	22-36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (HPLC)
Storage Temp.	room temp
UNSPSC	12352200

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