6-Fluoromevalonate

SIGMA/F2929 - ≥90% (GC), viscous liquid

Synonym: Tetrahydro-4-fluoromethyl-4-hydroxy-2H-pyran-2-one; ZR 3516

CAS Number: 2822-77-7
Empirical Formula (Hill Notation): C₆H₉FO₃
Molecular Weight: 148.13
MDL Number: MFCD08276919
Linear Formula: C₆H₉FO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-F2929-5MG	5 mg	$233.00 1/EA		Add To Favorites
45-F2929-25MG	25 mg	$886.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥90% (GC)
color	yellow tint
form	viscous liquid
InChI	1S/C6H9FO3/c7-4-6(9)1-2-10-5(8)3-6/h9H,1-4H2
InChI key	DPPMVKMESJJAJZ-UHFFFAOYSA-N
Quality Level	100
SMILES string	OC1(CF)CCOC(=O)C1
solubility	DMSO: ≥3 mg/mL
storage temp.	2-8°C

Application:	6-Fluoromevalonate has been used as a mevalonate pyrophosphate decarboxylase inhibitor: • to study the effect of mevalonate pathway inhibition on patient-derived brain tumor-initiating cells (BTICs) growth and self-renewal • to study its effect on induction of trained immunity by β-glucan in monocytes • to determine the effect of the mevalonate pathway (MVP) on ADP-ribosylation factor 6 (ARF6) activation
Biochem/physiol Actions:	Mevalonate-pyrophosphate decarboxylase inhibitor
Packaging:	5, 25 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥90% (GC)
Storage Temp.	2-8°C
UNSPSC	51111800

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