L-(−)-Fucose

SIGMA/F2252 - ≥98% (GC)

Synonym: 6-Deoxy-L-galactose

CAS Number: 2438-80-4
Empirical Formula (Hill Notation): C₆H₁₂O₅
Molecular Weight: 164.16
EC Number: 219-452-7
MDL Number: MFCD00135607
Linear Formula: C₆H₁₂O₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-F2252-10MG	10 mg	$29.70 1/EA	Add To Favorites
45-F2252-5G	5 g	$177.00 1/EA	Add To Favorites
45-F2252-25G	25 g	$780.00 1/EA	Add To Favorites
45-F2252-100G	100 g	$2150.00 1/EA	Add To Favorites

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This image depicts SKU: F2252-100G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98% (GC)
color	white
form	powder
InChI	1S/C6H12O5/c1-3(8)5(10)6(11)4(9)2-7/h2-6,8-11H,1H3/t3-,4+,5+,6-/m0/s1
InChI key	PNNNRSAQSRJVSB-KCDKBNATSA-N
mp	150-153 °C (lit.)
Quality Level	300
SMILES string	C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C=O
solubility	H₂O: soluble 50 mg/mL, clear to very slightly hazy
technique(s)	gas chromatography (GC): suitable

Application:	L-(−)-Fucose has been used: • as the non-haptenic sugar in lectin bead-binding assay to study its effects on the binding of immobilized lectins like peanut agglutinin (PNA) and Dolichos biflorus agglutinin (DBA) • as an internal standard to dilute the enzymatic hydrolysates for analytical methods • in the synthesis of fucosyl thioglycoside
Biochem/physiol Actions:	L-Fucose (6-Deoxy-L-galactose) is used in studies of fucoidan polysaccharides containing glycans. It is studied as a glycan modifying carbohydrate that generates antigenic sites recognized by IgE antibodies. L-Fucose is used as a substrate to identify, differentiate, and characterize enzymes such as fucosidase(s),l-fucose isomerase(s), and L-fucose dehydrogenase(s). It may be used to study organelles, and bacterial microcompartments, involved in the degradation of plant and algal cell wall sugars. L-Fucose may also be used as a reference compound in rare sugar identification and analysis.
Biochem/physiol Actions:	L-Fucose is broadly used as a food additive. It possesses anti-inflammatory effects. It can inhibit the cutaneous immune reaction and alveolar macrophage priming. L-fucose can also suppress tumor growth and tumorigenesis.
General description:	L-Fucose, a natural monosaccharide found in mammals, is an important component of several N- and O-linked glycans and glycolipids.
Other Notes:	To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Packaging:	10 mg in glass bottle
Packaging:	5, 25, 100 g in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98% (GC)
mp	150-153 °C (lit.)
UNSPSC	12352201

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