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R-(−)-Fluoxetine hydrochloride

SIGMA/F1678 - >98% (HPLC), solid

Synonym: (R)-N-Methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propylamine hydrochloride

CAS Number: 114247-09-5
Empirical Formula (Hill Notation): C17H18NOF3 · HCl
Molecular Weight: 345.79
MDL Number: MFCD04040065
Linear Formula: C17H18NOF3 · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F1678-5MG 5 mg
 $125.00
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45-F1678-25MG 25 mg
 $441.00
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assay >98% (HPLC)
color white
form solid
InChI 1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1
InChI key GIYXAJPCNFJEHY-PKLMIRHRSA-N
originator Eli Lilly
Quality Level 100 
SMILES string Cl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2
solubility H2O: soluble >10 mg/mL
storage condition desiccated
Application: R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:
• to study its effects on the embryoid body (EB) morphogenesis
• in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
• to study its effects as an endocrine disruption inducer in Pimephales promelas
Biochem/physiol Actions: Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.
Biochem/physiol Actions: Selective serotonin reuptake inhibitor.
Features and Benefits: This compound was developed by Eli Lilly . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here .
Packaging: 5, 25 mg in glass bottle
Purity >98% (HPLC)
UNSPSC 12352200

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