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Finasteride

SIGMA/F1293 - ≥98% (HPLC), powder

Synonym: N-(2-methyl-2-propyl)-3-oxo-4-aza-5α-androst-1-ene-17β-carboxamide; N-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamide; MK-906

CAS Number: 98319-26-7
Empirical Formula (Hill Notation): C23H36N2O2
Molecular Weight: 372.54
MDL Number: MFCD00869737
Linear Formula: C23H36N2O2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F1293-100MG 100 mg
 $127.00
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assay ≥98% (HPLC)
color white to beige
form powder
InChI 1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
InChI key DBEPLOCGEIEOCV-WSBQPABSSA-N
Quality Level 100 
SMILES string [H][C@@]12CC[C@@]3([H])[C@]4([H])CC[C@H](C(=O)NC(C)(C)C)[C@@]4(C)CC[C@]3([H])[C@@]1(C)C=CC(=O)N2
solubility DMSO: soluble >20 mg/mL
storage temp. room temp
Application: Finasteride has been used:
• as a component of L-15 media to investigate the effects of finasteride exposure on brain, liver and testis tissues
• in culture medium to treat tumor cells in vitro
• as a positive control to treat benign prostatic hyperplasia (BPH)
• to examine its effect on structural and molecular biology on the ventral prostate of senile mice
Biochem/physiol Actions: Finasteride can reduce serum and scalp dihydrotestosterone (DHT) by preventing the transformation of testosterone to DHT. It is usually used to manage benign prostate hyperplasia and pattern hair loss in male. Finasteride possesses androgen-distracting properties.
Biochem/physiol Actions: Selective 5α-reductase inhibitor; antiandrogen.
Packaging: 100 mg in glass bottle
Purity ≥98% (HPLC)
Storage Temp. room temp
UNSPSC 41116107

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