Synonym: 8-[4,4-bis(p-Fluorophenyl)butyl]-1-phenyl-1,3,8-triazino[4.5]decan-4-one; R 6218
CAS Number: 1841-19-6
Empirical Formula (Hill Notation): C29H31F2N3O
Molecular Weight: 475.57
EC Number: 217-418-6
MDL Number: MFCD00055137
Linear Formula: C29H31F2N3O
Product Type: Chemical
| assay |
≥98% (HPLC) |
| color |
white |
| form |
solid |
| InChI |
1S/C29H31F2N3O/c30-24-12-8-22(9-13-24)27(23-10-14-25(31)15-11-23)7-4-18-33-19-16-29(17-20-33)28(35)32-21-34(29)26-5-2-1-3-6-26/h1-3,5-6,8-15,27H,4,7,16-21H2,(H,32,35) |
| InChI key |
QOYHHIBFXOOADH-UHFFFAOYSA-N |
| originator |
Johnson & Johnson |
| Quality Level |
200  |
| SMILES string |
Fc1ccc(cc1)C(CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4)c5ccc(F)cc5 |
| solubility |
DMSO: ≥20 mg/mL |
| |
ethanol: soluble |
| |
H2O: insoluble |
| storage temp. |
room temp |
| Application: |
Fluspirilene has been used as a neuroleptic drug to study its effects on human ether-a-go-go related gene (HERG). |
| Application: |
Fluspirilene has been used to study its cytotoxicity effect on malignant glioma. |
| Biochem/physiol Actions: |
Fluspirilene has a potential to inhibit the activity of cyclin-dependent kinase 2 (CDK2). It is an effective anti-cancer agent used for treating human hepatocellular carcinoma. |
| Biochem/physiol Actions: |
Fluspirilene is a dopamine receptor antagonist. It also acts as a calcium channel blocker. Fluspirilene is an antipsychotic agent and exhibits neuoleptic properties. It exhibits therapeutic effects against glioblastoma and Schizophrenia. |
| Features and Benefits: |
This compound was developed by Johnson & Johnson . To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here . |
| Packaging: |
10, 50 mg in glass bottle |
| RIDADR |
NONH for all modes of transport |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| Purity |
≥98% (HPLC) |
| Storage Temp. |
room temp |
| UNSPSC |
12352200 |
