Factor Va human
SIGMA/F0931 - ≥1500 units/mg protein
MDL Number: MFCD01093755
Product Type: Chemical
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| biological source | human |
| form | solution |
| mol wt | 168 kDa |
| Quality Level | 200  |
| shipped in | wet ice |
| specific activity | ≥1500 units/mg protein |
| storage temp. | −20°C |
| technique(s) | ligand binding assay: suitable |
| UniProt accession no. | P12259  |
| Biochem/physiol Actions: | Factor V is a key component in blood coagulation systems, where deficiencies can inhibit thrombin generation and affect hemostasis. It has been used in studies of coagulopathic bleeding which occurs following injury and is a leading cause of hospital deaths. |
| Biochem/physiol Actions: | Factor Va serves as a receptor and positive effector of factor Xa. Hence it can efficiently help in the conversion of prothrombin to thrombin. |
| Disclaimer: | RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization. |
| General description: | Factor V, a glycoprotein is usually seen in the alpha granules of platelets and in plasma. |
| General description: | Factor Va is the activated form of factor V and the cofactor of Xa. It is a component of the prothrombinase complex. |
| Other Notes: | One unit is equivalent to the Factor V activity in 1.0 mL of normal human plasma at pH 7.4 at 37 °C. |
| Other Notes: | View this factors role in the Coagulation Cascade |
| Physical form: | Aqueous solution containing 50% (v/v) glycerol and 5mM CaCl2 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: ≥1500 units/mg protein |
| Storage Temp. | −20°C |
| UNSPSC | 12352202 |