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Fusidic acid

SIGMA/F0756

Synonym: Ramycin

CAS Number: 6990-06-3
Empirical Formula (Hill Notation): C31H48O6
Molecular Weight: 516.71
EC Number: 230-256-0
MDL Number: MFCD00865135
Linear Formula: C31H48O6
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F0756-1G 1 g
 $459.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F0756-1G

 

InChI 1S/C31H48O6/c1-17(2)9-8-10-20(28(35)36)26-22-15-24(34)27-29(5)13-12-23(33)18(3)21(29)11-14-30(27,6)31(22,7)16-25(26)37-19(4)32/h9,18,21-25,27,33-34H,8,10-16H2,1-7H3,(H,35,36)/b26-20-/t18-,21-,22-,23+,24+,25-,27-,29-,30-,31-/m0/s1
InChI key IECPWNUMDGFDKC-MZJAQBGESA-N
Quality Level 200 
SMILES string [H][C@@]12CC[C@@]3(C)[C@@]([H])([C@H](O)C[C@@]4([H])C([C@H](C[C@]34C)OC(C)=O)=C(/CCC=C(C)C)C(O)=O)[C@@]1(C)CC[C@@H](O)[C@H]2C
storage temp. 2-8°C
Application: Fusidic acid has been used:
• as a standard in thin-layer chromatography (TLC)-densitometric method
• to study its ability to bind to human serum albumin
• as an antibiotic in combination with tannic acid to determine minimum inhibitory concentrations (MIC) in methicillin-resistant Staphylococcus aureus (MRSA)
Biochem/physiol Actions: Fusidic acid is a tetracyclic triterpenoid with antibiotic activity against Gram-positive bacteria. It is derived from Fusidium coccineum. It shows its activity against anaerobes, corynebacterial, Nocardia, and Neisseria species. Fusidic acid exhibits therapeutic effects against Staphylococcal infections, skin infections.
Biochem/physiol Actions: Suppresses nitric oxide lysis of pancreatic islet cells. Inhibits protein synthesis in prokaryotes by inhibiting the ribosome-dependent activity of G factor and translocation of peptidyl-tRNA.
Biochem/physiol Actions: Suppresses nitric oxide lysis of pancreatic islet cells; inhibits protein synthesis in prokaryotes.
Packaging: 1 g in poly bottle
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P264 - P270 - P301 + P312 + P330 - P501
Hazard Codes Xn
Risk Statements 22
Safety Statements 36
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352106

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