β-Estradiol
SIGMA/E8875 - ≥98%
Synonym: 1,3,5-
CAS Number: 50-28-2
Empirical Formula (Hill Notation): C18H24O2
Molecular Weight: 272.38
EC Number: 200-023-8
MDL Number: MFCD00003693
Linear Formula: C18H24O2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E8875-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E8875-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E8875-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E8875-250MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E8875-5G
| assay | ≥98% |
| biological source | synthetic (organic) |
| form | powder |
| InChI | 1S/C18H24O2/c1-18-9-8-14- |
| InChI key | VOXZDWNPVJITMN-ZBRFXRBCSA |
| mp | 176-180 °C (lit.) |
| Quality Level | 300  |
| shipped in | ambient |
| SMILES string | O[C@H]1CC[C@@]2([H])[C@]3 |
| solubility | ethanol: 50 mg/mL, clear, colorless |
| sterility | non-sterile |
| storage temp. | room temp |
| technique(s) | cell culture | mammalian: suitable |
| Application: | β-Estradiol has been used: • for the in vitro maturation of bovine cumulus-oocyte complexes (COCs) • as a supplement in in vitro maturation medium (IVM), which is used as a control medium • in estrogen-induction assay |
| Biochem/physiol Actions: | The major estrogen secreted by the premenopausal ovary. |
| Biochem/physiol Actions: | The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation. |
| Features and Benefits: | This compound is featured on the Acetylcholine Receptors (Nicotinic) and Nuclear Receptors (Steroids) pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here . |
| General description: | β-Estradiolis a natural steroid estrogen and a female sex hormone. It is an essential component of the female menstrual cycle and plays an important role in the growth and maintenance of the reproductive system. |
| Packaging: | 1, 5, 25, 100 g in glass bottle |
| Packaging: | 250 mg in glass bottle |
| Symbol |   GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H351 - H360FD - H362 - H410 |
| Precautionary statements | P201 - P202 - P260 - P263 - P273 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 60-63-40-64 |
| Safety Statements | 53-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98% |
| mp | 176-180 °C (lit.) |
| Storage Temp. | room temp |
| UNSPSC | 12352104 |