Epoxy-activated−Sepharose™ 6B
SIGMA/E6754 - lyophilized powder
Synonym: Epoxy-
MDL Number: MFCD00163561
Product Type: Chemical
Epoxy-activated matrices can be used to couple sugars and other carbohydrates via stable ether linkages to hydroxyl groups. Other ligands can be coupled through hydroxyl, amino or thiol groups.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E6754-5G
| extent of labeling | 19-40 μmol per mL |
| form | lyophilized powder |
| matrix | Sepharose 6B |
| matrix active group | epoxy |
| matrix attachment | through epoxy to hydroxyl |
| matrix spacer | 12 atoms |
| particle size | 45—165 μm |
| Quality Level | 200  |
| storage temp. | 2-8°C |
| swelling | 1 g swells to 3.0-5.0 mL |
| technique(s) | affinity chromatography: suitable |
| Application: | Epoxy-activated-Sepharose™ is used in affinity chromatography, protein chromatography, and activated/functionalized matrices. Epoxy-activated-Sepharose™ has been used to obtain a monoclonal antibody against the prokaryotically expressed foot-and-mouth disease virus (FMDV) non-structural protein (NSP) 3B as well as to study B meningococcal disease. |
| General description: | when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether. |
| Legal Information: | Sepharose is a trademark of Cytiva |
| Other Notes: | Ligand: 1,4-bis(2:3-Epoxypropoxy) Attachment: one epoxy group Spacer: provides a 12-atom spacer when ligands are coupled to free epoxy groups. Linkage is a stable, uncharged ether. |
| Packaging: | 5, 15 g in poly bottle |
| Physical form: | Lyophilized powder |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 41106500 |