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Dexamethasone

SIGMA/D4902 - powder, BioReagent, suitable for cell culture, ≥97%

Synonym: (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F

CAS Number: 50-02-2
Empirical Formula (Hill Notation): C22H29FO5
Molecular Weight: 392.46
EC Number: 200-003-9
MDL Number: MFCD00064136
Linear Formula: C22H29FO5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D4902-25MG 25 mg
 $50.40
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45-D4902-100MG 100 mg
 $113.00
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45-D4902-500MG 500 mg
 $379.00
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45-D4902-1G 1 g
 $560.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D4902-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D4902-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D4902-25MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D4902-500MG

 

assay ≥97%
biological source synthetic
form powder
InChI 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
InChI key UREBDLICKHMUKA-CXSFZGCWSA-N
mp 262-264 °C (lit.)
potency 4-500 ng/mL
product line BioReagent
Quality Level 200 
shipped in ambient
SMILES string C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
solubility methanol: 25 mg/mL
storage temp. 2-8°C
technique(s) cell culture | mammalian: suitable
  single cell analysis: suitable
Application: Dexamethasone is used to study apoptosis, cell signaling pathways, cell differentiation and gene expression.
Biochem/physiol Actions: Glucocorticoid anti-inflammatory agent
Biochem/physiol Actions: Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
Biochem/physiol Actions: It is poorly metabolized in the body and has great affinity and bioavailability.
Packaging: 1 g in glass bottle
Packaging: 25, 100, 500 mg in glass bottle
Packaging: Bottomless glass bottle. Contents are inside inserted fused cone.
Physical form: powder 2-8 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw
Preparation Note: To prepare 20 μg/ml stock solution, add 1ml absolute ethanol per mg product; gently swirl to dissolve. Add 49 ml sterile medium per ml of ethanol added, while mixing, to acheive final concentration of 20 μg/ml.
Purity ≥97%
mp 262-264 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 12352209

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