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Duramycin from Streptoverticillium cinnamoneus

SIGMA/D3168 - ≥90.0%

Synonym: Duramycin; Lancovutide

CAS Number: 1391-36-2
Empirical Formula (Hill Notation): C89H125N23O25S3
Molecular Weight: 2013.28
MDL Number: MFCD00133301
Linear Formula: C89H125N23O25S3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D3168-10MG 10 mg
 $586.00
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This image is provided for informative purposes only and does not represent an actual product label. It should not be used as a substitute for official product labeling.

 

antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
assay ≥90.0%
form powder
mode of action protein synthesis | interferes
Quality Level 200 
solubility 0.1 M HCl: 10 mg/mL
storage temp. 2-8°C
Application: Duramycin is used to study chloride secretion by cardial, pancreatic and airway epithelial voltage-gated ion channels. It is used to study cystic fibrosis and as a novel phosphatidylethanolamine-binding molecular probe. It is used to stimulate sodium transport in cultured human colonic epithelia.
Biochem/physiol Actions: Duramycin is the smallest known polypeptide since it has only 19 amino acids. It has a defined 3-dimensional binding structure. Duramycin binds phosphatidylethanolamine (PtdE) at a 1:1 ratio with high affinity and exclusive specificity. It enhances chloride secretion in airway epithelium.
General description: Chemical structure: tetracycline
Other Notes: Keep container tightly closed in a dry and well-ventilated place.
Packaging: 10 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥90.0%
Storage Temp. 2-8°C
UNSPSC 51102829

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