Dimethyl sulfoxide
SIGMA/D2438 - sterile-filtered, BioPerformance Certified, meets EP, USP testing specifications, suitable for hybridoma
Synonym: DMSO
CAS Number: 67-68-5
Empirical Formula (Hill Notation): C2H6OS
Molecular Weight: 78.13
EC Number: 200-664-3
MDL Number: MFCD00002089
Linear Formula: (CH3)2SO
Product Type: Chemical
| agency | USP XXIV |
| meets EP testing specifications | |
| meets USP testing specifications | |
| autoignition temp. | 573 °F |
| bp | 189 °C (lit.) |
| color | colorless |
| density | 1.10 g/mL (lit.) |
| expl. lim. | 42 %, 63 °F |
| form | liquid |
| grade | BioPerformance Certified |
| impurities | ≤0.1% water |
| InChI | 1S/C2H6OS/c1-4(2)3/h1-2H3 |
| InChI key | IAZDPXIOMUYVGZ-UHFFFAOYSA |
| mp | 16-19 °C (lit.) |
| Quality Level | 400  |
| refractive index | n |
| SMILES string | CS(C)=O |
| solubility | H2O: miscible (completely) |
| sterility | sterile-filtered |
| technique(s) | cell culture | hybridoma: suitable |
| cryopreservation: suitable | |
| vapor density | 2.7 (vs air) |
| vapor pressure | 0.42 mmHg ( 20 °C) |
| Application: | Dimethyl sulfoxide has been used as a vehicle control to culture and induce hepatic stellate cells (HSCs) activation in vivo. It has also been used to prepare a stock solution to study the cytotoxicity of ferulic acid (FA) on nucleus pulposus (NP) cells. |
| Disclaimer: | Supercools easily and remelts slowly at room temperature. Solidified product can be re-liquified by warming to room temperature without detriment to the product. |
| Features and Benefits: | Ready-to-use sterile filtered product conveniently packaged in septum screw-capped amber bottles. Meets USP and EP testing requirements |
| General description: | Dimethyl sulfoxide (DMSO) is an aprotic solvent. Therapeutic and toxic molecules that are not soluble in water are often soluble in DMSO. Liquid nitrogen used in conjunction with a cryoprotective agent such as DMSO is a widely used method for preserving cells. DMSO is used to prepare stock solutions of various molecules and is also used as a control for these molecules. It has been used in cell migration assay for dissolving post-migration cells. BPC-tested DMSO also meets the requirements of biotechnology and tissue engineering applications. |
| RIDADR | NA 1993 / PGIII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 188.6 °F - closed cup |
| Flash Point(C) | 87 °C - closed cup |
| bp | 189 °C (lit.) |
| mp | 16-19 °C (lit.) |
| Density | 1.10 g/mL (lit.) |
| Refractive Index | n |
| UNSPSC | 12191502 |