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N6,2′-O-Dibutyryladenosine 3′,5′-cyclic monophosphate sodium salt

SIGMA/D0627 - ≥96% (HPLC), powder

Synonym: Bucladesine sodium salt; Dibutyryl cAMP sodium salt; Dibutyryl cyclic-AMP sodium salt

CAS Number: 16980-89-5
Empirical Formula (Hill Notation): C18H23N5NaO8P
Molecular Weight: 491.37
EC Number: 241-059-4
MDL Number: MFCD00005843
Linear Formula: C18H23N5O8PNa
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-D0627-25MG 25 mg
 $84.90
1/EA		 Add To Favorites
45-D0627-100MG 100 mg
 $240.00
1/EA		 Add To Favorites
45-D0627-250MG 250 mg
 $387.00
1/EA		 Add To Favorites
45-D0627-1G 1 g
 $1250.00
1/EA		 Add To Favorites
45-D0627-5X1G 1 g
 $4940.00
5/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D0627-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D0627-25MG

 

assay ≥96% (HPLC)
biological source synthetic (organic)
color off-white
form powder
impurities ≤0.5% Cyclic AMP
  ≤3% monobutyryl derivatives
InChI 1S/C18H24N5O8P.Na/c1-3-5-11(24)22-16-13-17(20-8-19-16)23(9-21-13)18-15(30-12(25)6-4-2)14-10(29-18)7-28-32(26,27)31-14;/h8-10,14-15,18H,3-7H2,1-2H3,(H,26,27)(H,19,20,22,24);/q;+1/p-1/t10-,14-,15-,18-;/m1./s1
InChI key KRBZRVBLIUDQNG-JBVYASIDSA-M
Quality Level 200 
SMILES string [Na+].CCCC(=O)Nc1ncnc2n(cnc12)[C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3OC(=O)CCC
solubility H2O: 100 mg/mL
storage temp. −20°C
Application: Dibutyryl CAMP is a cell-permeable CAMP analogue that activates CAMP dependent protein kinase (PKA) or the CAMP/PKA signaling pathway. Dibutyryl CAMP is used as a morphological differentiation inducer and cell signaling modulator in cells such as Schwann cells. Dibutyrl cAMP is used in a variety of differentiation studies, such as neuron differentiation / neuronal differentiation.
Biochem/physiol Actions: Cell-permeable cAMP analog that activates cAMP dependent protein kinase (PKA).
Disclaimer: Loses 2′-O-butyryl group at pH 8.5
Other Notes: 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research 
Packaging: 1 g in poly bottle
Packaging: 25, 100, 250 mg in poly bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥96% (HPLC)
Storage Temp. −20°C
UNSPSC 41106305

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