Cholesterol

SIGMA/C8667 - Sigma Grade, ≥99%

Synonym: 3β-Hydroxy-5-cholestene; 5-Cholesten-3β-ol

CAS Number: 57-88-5
Empirical Formula (Hill Notation): C₂₇H₄₆O
Molecular Weight: 386.65
EC Number: 200-353-2
MDL Number: MFCD00003646
Linear Formula: C₂₇H₄₆O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-C8667-500MG	500 mg	$53.30 1/EA	Add To Favorites
45-C8667-1G	1 g	$67.50 1/EA	Add To Favorites
45-C8667-5G	5 g	$116.00 1/EA	Add To Favorites
45-C8667-25G	25 g	$385.00 1/EA	Add To Favorites
45-C8667-100G	100 g	$1230.00 1/EA	Add To Favorites

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This image depicts SKU: C8667-25G

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99%
biological source	sheep wool
bp	360 °C (lit.)
density	1.067 g/mL at 25 °C (lit.)
form	powder
grade	Sigma Grade
InChI	1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI key	HVYWMOMLDIMFJA-DPAQBDIFSA-N
mp	147-149 °C (lit.)
Quality Level	200
shipped in	ambient
SMILES string	CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
solubility	water: soluble 0.00003 g/L at 20 °C
storage temp.	−20°C

Application:	Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.
Application:	Standard for chromatography
Biochem/physiol Actions:	Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.
Biochem/physiol Actions:	Major component of all biological membranes; ~25% of total brain lipid is cholesterol.
Packaging:	1, 5, 25, 100 g in poly bottle
Packaging:	500 mg in poly bottle
Preparation Note:	Cholesterol monohydrate yields a clear, colorless to faint yellow solution in hot alcohol. It is also soluble in acetone, dioxane, ethyl acetate, benzene, petroleum ether, oils, fats, and in aqueous solutions of bile salts. Solutions should be protected from light.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99%
bp	360 °C (lit.)
mp	147-149 °C (lit.)
Density	1.067 g/mL at 25 °C (lit.)
Storage Temp.	−20°C
UNSPSC	12352111

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