Anti-CXCR4 (Fusin) (182-196) antibody produced in rabbit
SIGMA/C8352 - IgG fraction of antiserum, buffered aqueous solution
MDL Number: MFCD01092337
Product Type: Chemical
Immunoblotting
Western blot analysis of CXCR4 in HeLa total cell lysate with Anti-CXCR4 (EL) (Cat. No. C8352) at 1:1,000 dilution.
Western blot analysis of CXCR4 in HeLa total cell lysate with Anti-CXCR4 (EL) (Cat. No. C8352) at 1:1,000 dilution.
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| biological source | rabbit |
| clone | polyclonal |
| conjugate | unconjugated |
| form | buffered aqueous solution |
| Quality Level | 200  |
| shipped in | dry ice |
| species reactivity | human |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| technique(s) | western blot: 0.5-1 μg/mL using human HeLa cell extract |
| UniProt accession no. | P61073  |
| Application: | Anti-CXCR4 (Fusin) (182-196) antibody may be used in immunoblotting at a working antibody concentration of 0.5 - 1 μg/ml using human HeLa cell extract. It can also be used in immunohistochemistry. |
| Disclaimer: | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
| General description: | Chemokine receptor CXCR-4 also refers as fusin or LESTR is a protein that belongs to G-protein coupled receptor 1 family. It is an essential cofactor for T cell-tropic HIV viruses into CD4+ cells. N-Terminal domain and second extracellular loop of the protein act as a HIV binding sites. Anti-CXCR4 (Fusin) (182-196) antibody can be used to block HIV-1 and HIV-2 fusion and infection of human target cells. Rabbit anti-CXCR4 (Fusin) (182-196) antibody reacts specifically with human CXCR4. |
| Immunogen: | synthetic peptide corresponding to amino acids 182-196 of the second extracellular loop of human CXCR4. |
| Other Notes: | The antigen (receptor) is also termed fusin, LESTER and HUMSTR. |
| Physical form: | Solution in phosphate buffered saline containing 0.02% sodium azide. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | −20°C |
| UNSPSC | 12352203 |