Caffeic acid phenethyl ester

SIGMA/C8221 - ≥97% (HPLC), powder

Synonym: CAPE

CAS Number: 104594-70-9
Empirical Formula (Hill Notation): C₁₇H₁₆O₄
Molecular Weight: 284.31
MDL Number: MFCD00866470
Linear Formula: C₁₇H₁₆O₄
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-C8221-1G	1 g	$702.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥97% (HPLC)
biological source	synthetic
color	off-white
form	powder
InChI	1S/C17H16O4/c18-15-8-6-14(12-16(15)19)7-9-17(20)21-11-10-13-4-2-1-3-5-13/h1-9,12,18-19H,10-11H2/b9-7+
InChI key	SWUARLUWKZWEBQ-VQHVLOKHSA-N
Quality Level	200
SMILES string	Oc1ccc(C=CC(=O)OCCc2ccccc2)cc1O
solubility	DMSO: soluble
	ethanol: soluble
	ethyl acetate: 50 mg/mL
storage condition	protect from light
storage temp.	−20°C

Application:	Caffeic acid phenethyl ester (CAPE) has been used to determine the effect of CAPE in hyperthyroidism, as a component of culture media to measure the cytotoxicity of breast cancer cell line MDA-MB-231, to study its effects on amiodarone-induced pulmonary fibrosis in rats.
Biochem/physiol Actions:	Caffeic acid phenethyl ester is a specific inhibitor of the nuclear transcription factor NF-κB.
Biochem/physiol Actions:	CAPE exhibits several properties such as anticarcinogenic, immunomodulatory activities, antioxidant, antiviral, anti-inflammatory, hypoglycaemic effect, cardioprotective and inhibits gastric secretion. It also has an inhibitory effect on fibroblasts growth factor type 2 (FGF-2), a tumor growth factor in breast cancer.
Features and Benefits:	This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm .

Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥97% (HPLC)
Storage Temp.	−20°C
UNSPSC	12352108

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